Periodontal disease and adverse pregnancy outcomes

被引:27
作者
Shub, Alexis
Swain, Jonathan R.
Newnham, John P.
机构
[1] Univ Western Australia, Sch Womens & Infants Hlth, Subiaco, WA 6008, Australia
[2] Univ Western Australia, Sch Dent, Perth, WA 6009, Australia
[3] Women & Infants Res Fdn, Perth, WA, Australia
[4] Oral Hlth Ctr Western Australia, Perth, WA, Australia
基金
英国医学研究理事会;
关键词
pregnancy; periodontal disease; preterm birth; intrauterine growth restriction;
D O I
10.1080/14767050600797749
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Periodontal disease is a common infectious disease in women of reproductive age. The disease is often not diagnosed and in studies of over 10 000 women has been associated with preterm birth, small for gestational age newborns, and preeclampsia. It has been shown in a smaller number of women that treatment of periodontal disease may reduce the rate of preterm birth. The pregnancy complications of periodontal disease may be due to lipopolysaccharide from the periodontal pockets inciting prostaglandin pathways controlling parturition. Three large randomized controlled trials of treatment of periodontal disease are underway and may provide confirmation of the importance of periodontal disease in causing complications of pregnancy.
引用
收藏
页码:521 / 528
页数:8
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