High frequency of EEG and MRI brain abnormalities in panic disorder

被引：52

作者：

Dantendorfer, K ^{[1
]}

Prayer, D ^{[1
]}

Kramer, J ^{[1
]}

Amering, M ^{[1
]}

Baischer, W ^{[1
]}

Berger, P ^{[1
]}

Schoder, M ^{[1
]}

Steinberger, K ^{[1
]}

Windhaber, J ^{[1
]}

Imhof, H ^{[1
]}

Katschnig, H ^{[1
]}

机构：

[1] UNIV VIENNA,DEPT RADIOL,A-1090 VIENNA,AUSTRIA

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 1996年 / 68卷 / 01期

关键词：

anxiety; morphologic brain abnormalities; septo-hippocampal system;

D O I：

10.1016/S0925-4927(96)03003-X

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The frequency and quality of brain abnormalities in panic disorder (PD) were assessed with magnetic resonance imaging (MRI). The use of electroencephalography (EEG) to detect PD patients with a high probability of morphologic brain abnormalities was also explored. Consecutive PD patients (n = 120) were screened with routine EEG examinations and were divided into the following subgroups on the basis of their EEG findings: patients with non-epileptic EEG abnormalities (EEG-A group, n = 28), matched patients with normal EEG results (EEG-N group, n = 28) and matched healthy controls (n = 28). PD patients showed a higher than expected rate of non-epileptic EEG abnormalities (29.2%; 35 of 120). EEG screening was effective in identifying patients with a high probability of morphologic brain abnormalities. MRI abnormalities were found in 60.7% of the EEG-A patients, 17.9% of the EEG-N patients, and only 3.6% of the controls. A high frequency of septo-hippocampal abnormalities was found. Further research should focus on attempts to subtype PD on the basis of neuroanatomic and functional brain abnormalities. Copyright (C) 1996 Elsevier Science Ireland Ltd.

引用

页码：41 / 53

页数：13

共 78 条

[1] COMPUTED EEG ABNORMALITIES IN PANIC DISORDER WITH AND WITHOUT PREMORBID DRUG-ABUSE [J].