Evaluation of available IgE-binding epitope data and its utility in bioinformatics

被引：40

作者：

Bannon, Gary A.

Ogawa, Tadashi

机构：

[1] Monsanto Co, St Louis, MO 63167 USA

[2] Kansai Univ Welf Sci, Osaka, Japan

来源：

MOLECULAR NUTRITION & FOOD RESEARCH | 2006年 / 50卷 / 07期

关键词：

allergen; crossreactivity; conformational epitope; genetic engineering; linear epitope;

D O I：

10.1002/mnfr.200500276

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

This paper reviews the role played by IgE-binding epitopes in eliciting clinical symptoms, the types of IgE-binding epitopes in allergenic proteins, the methods used to identify IgE-binding epitopes, and the availability of IgE-binding epitopes in allergenic sources. Finally, bioinformatics methods to assess protein allergenicity using knowledge of IgE-binding epitopes are discussed.

引用

页码：638 / 644

页数：7

共 47 条

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