No change in parasite genotype during single episodes of Plasmodium falciparum malaria in Gabonese children

被引：7

作者：

Missinou, MA

Kun, JFJ

Kremsner, PG

机构：

[1] Univ Tubingen, Inst Trop Med, Dept Parasitol, D-72074 Tubingen, Germany

[2] Albert Schweitzer Hosp, Med Res Unit, Lambarene, Gabon

来源：

PARASITOLOGY RESEARCH | 2004年 / 93卷 / 04期

关键词：

D O I：

10.1007/s00436-004-1137-1

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Patients living in endemic areas can carry a mixture of Plasmodium falciparum genotypes. To investigate the genetic composition of parasite genotypes in malaria patients during the acute phase of the infection, we performed close follow-ups of 17 Gabonese pediatric patients aged 2-7 years. Capillary blood samples were taken on admission and every 4-6 h after the start of quinine therapy. Merozoite surface protein 2 (MSP2) genotypes were used to assess the parasites' genetic characteristics in each sample. We found that each patient carried parasites with the same genotypic pattern throughout the infection.

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收藏

页码：322 / 327

页数：6

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