Fourier-domain optical coherence tomography: recent advances toward clinical utility

被引：103

作者：

Bouma, Brett E. ^{[1
]}

Yun, Seok-Hyun ^{[1
]}

Vakoc, Benjamin J. ^{[1
]}

Suter, Melissa J. ^{[1
]}

Tearney, Guillermo J. ^{[1
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med,MGH, Harvard Mit Div Hlth Sci & Technol,Wellman Ctr Ph, Boston, MA 02114 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2009年 / 20卷 / 01期

基金：

美国国家卫生研究院;

关键词：

SPECTRAL-DOMAIN; HIGH-RESOLUTION; SWEPT-SOURCE; BIREFRINGENCE CHARACTERIZATION; MOLECULAR CONTRAST; BIOLOGICAL TISSUE; DEPTH-DEGENERACY; FREQUENCY; PHASE; LASER;

D O I：

10.1016/j.copbio.2009.02.007

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

With the advent of Fourier-domain techniques, optical coherence tomography (OCT) has advanced from high-resolution 'point' imaging over small fields-of-view to comprehensive microscopic imaging over three-dimensional volumes that are comparable to the dimensions of luminal internal organs. This advance has required the development of new lasers, improved spectrometers, minimally invasive catheters and endoscopes, and novel optical and signal processing strategies. In recent cardiovascular, ophthalmic, and gastrointestinal clinical studies, the capabilities of Fourier-domain OCT have enabled a new paradigm for diagnostic screening of large tissue areas, which addresses the shortcomings of existing technologies and focal biopsy.

引用

页码：111 / 118

页数：8

共 81 条

[1]

Phase-sensitive optical coherence tomography at up to 370,000 lines per second using buffered Fourier domain mode-locked lasers [J].