Molecular mimicry between Helicobacter pylori and the host

被引：137

作者：

Appelmelk, BJ

Negrini, R

Moran, AP

Kuipers, EJ

机构：

[1] SPEDALI CIVIL BRESCIA,BIOTECHNOL LAB,I-25125 BRESCIA,ITALY

[2] NATL UNIV IRELAND UNIV COLL GALWAY,DEPT MICROBIOL,GALWAY,IRELAND

[3] VANDERBILT UNIV,DIV INFECT DIS,NASHVILLE,TN 37232

[4] FREE UNIV AMSTERDAM,DEPT GASTROENTEROL,NL-1081 BT AMSTERDAM,NETHERLANDS

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 02期

关键词：

D O I：

10.1016/S0966-842X(96)10084-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Helicobacter pylori lipopolysaccharide (LPS) expresses Lewis x and Lewis y blood group antigens that are identical to those occurring in the human gastric mucosa. During infection, antibodies against LPS, which bind to host Lewis antigens, may be induced. These consequently recognize gastric glycoprotein targets and cause autoimmune inflammation.

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收藏

页码：70 / 73

页数：4

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