Signal transduction in development: Holding the key

被引：20

作者：

Harwood, AJ

机构：

[1] UCL, MRC, Mol Cell Biol Lab, London WC1E 6BT, England

[2] UCL, Dept Biol, London WC1E 6BT, England

来源：

DEVELOPMENTAL CELL | 2002年 / 2卷 / 04期

关键词：

D O I：

10.1016/S1534-5807(02)00156-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The unrelated GSK-3 and CK1 families stand out among the protein kinases because of their phosphorylated substrate recognition sites. Two papers in the March 22nd issue of Cell highlight the importance of the priming phosphorylation for signal transduction during development.

引用

页码：384 / 385

页数：2

共 10 条

[1] The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction
Cohen, P
[J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1999, 354 (1382) : 485 - 495
[2] FLOTOW H, 1990, J BIOL CHEM, V265, P14264
[3] Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex
Gao, ZH
Seeling, JM
Hill, V
Yochum, A
Virshup, DM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (03) : 1182 - 1187
[4] Regulation of GSK-3: A cellular multiprocessor
Harwood, AJ
[J]. CELL, 2001, 105 (07) : 821 - 824
[5] Hedgehog signaling in animal development: paradigms and principles
Ingham, PW
McMahon, AP
[J]. GENES & DEVELOPMENT, 2001, 15 (23) : 3059 - 3087
[6] Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
Liu, CM
Li, YM
Semenov, M
Han, C
Baeg, GH
Tan, Y
Zhang, ZH
Lin, XH
He, X
[J]. CELL, 2002, 108 (06) : 837 - 847
[7] Polakis P, 2000, GENE DEV, V14, P1837
[8] Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1
Price, MA
Kalderon, D
[J]. CELL, 2002, 108 (06) : 823 - 835
[9] Casein kinase I: From obscurity to center stage
Vielhaber, E
Virshup, DM
[J]. IUBMB LIFE, 2001, 51 (02) : 73 - 78
[10] Mechanisms of Wnt signaling in development
Wodarz, A
Nusse, R
[J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1998, 14 : 59 - 88

← 1 →