Enantiodiscrimination by NMR spectroscopy

被引:50
作者
Uccello-Barretta, Gloria [1 ]
Balzano, Federica [1 ]
Salvadori, Piero [1 ]
机构
[1] Univ Pisa, Dipartimento Chim & Chim Ind, I-56126 Pisa, Italy
关键词
D O I
10.2174/138161206778743628
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The analysis of enantiorecognition processes involves the detection of enantiomeric species as well as the study of chiral discrimination mechanisms. In both fields Nuclear Magnetic Resonance (NMR) spectroscopy plays a fundamental role, providing several tools, based on the use of suitable chiral auxiliaries, for observing distinct signals of enantiomers and for investigating the complexation phenomena involved in enantiodiscrimination processes.
引用
收藏
页码:4023 / 4045
页数:23
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