DTX5c, a new OA sulphate ester derivative from cultures of Prorocentrum belizeanum

被引：31

作者：

Cruz, Patricia G. ^{[1
]}

Daranas, Antonio H. ^{[1
]}

Fernandez, Jose J. ^{[1
]}

Souto, Maria L. ^{[1
]}

Norte, Manuel ^{[1
]}

机构：

[1] Univ La Laguna, Inst Univ Bioorgan Antonio Gonzalez, E-38206 San Cristobal la Laguna, Tenerife, Spain

来源：

TOXICON | 2006年 / 47卷 / 08期

关键词：

marine toxins; DSP; dinophysistoxins; okadaic acid; DTX5c;

D O I：

10.1016/j.toxicon.2006.03.005

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Prorocentrum belizeanum is a dinoflagellate known for its okadaic acid (OA) and dinophysitoxins (DTXs) production, both OA and DTX are polyether toxins of the Diarrhetic Shellfish Poisoning (DSP) group. We have recently published the isolation of a new diol-ester of okadaic acid from cultures of P. belizeanum. On this occasion we present a new sulphated water-soluble derivative, DTX-5c, isolated from this microalga, whose structure was established on the basis of its spectroscopical data. (c) 2006 Elsevier Ltd. All rights reserved.

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收藏

页码：920 / 924

页数：5

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