Okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum Faust isolated from the Belizean coral reef ecosystem

被引：48

作者：

Morton, SL

Moeller, PDR

Young, KA

Lanoue, B

机构：

[1] Bigelow Lab Ocean Sci, Ctr Culture Marine Phytoplankton, W Boothbay Harbor, ME 04575 USA

[2] Natl Marine Fisheries Serv, SE Fisheries Sci Ctr, Charleston Lab, Charleston, SC 29422 USA

来源：

TOXICON | 1998年 / 36卷 / 01期

关键词：

D O I：

10.1016/S0041-0101(97)00054-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A species of epiphytic Prorocentrum (Dinophyta, Prorocentrales), collected from the macroalga Dictyota dichotoma, was brought into culture. Based on morphological characteristics, this isolate was identified as Prorocentrum belizeanum. Analysis of the culture extract using high-performance liquid chromatography and liquid chromatography-mass spectrometry indicated the production of okadaic acid, a toxic polyether linked with the human diseases, diarrhetic shellfish poisoning and ciguatera fish poisoning. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：201 / 206

页数：6

共 14 条

[1]

AIKMAN KE, 1993, DEV MAR BIO, V3, P463

[2] IDENTIFICATION OF OKADAIC ACID FROM A CARIBBEAN DINOFLAGELLATE, PROROCENTRUM-CONCAVUM [J].