HPLC residues of enrofloxacin and ciprofloxacin in eggs of laying hens

被引：52

作者：

Gorla, N ^{[1
]}

Chiostri, E ^{[1
]}

Ugnia, L ^{[1
]}

Weyers, A ^{[1
]}

Giacomelli, N ^{[1
]}

Davicino, R ^{[1
]}

Ovando, HG ^{[1
]}

机构：

[1] UNIV NACL RIO CUARTO,FAC AGRONOMIA & VET,FARMACOL DPTO CLIN ANIM,RA-5800 RIO CUARTO,CBA,ARGENTINA

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 1997年 / 8卷 / 04期

关键词：

fluoroquinolones; enrofloxacin; ciprofloxacin; residues; eggs;

D O I：

10.1016/S0924-8579(97)00018-6

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Eggs of 12 laying hens with 5 mg/kg/day oral administration of 5% enrofloxacin (EFX) or ciprofloxacin (CFX) solution during 5 days contained residues from 0.02 to 1.98 mu g/g (EFX) or 0.14 to 0.28 mu g/g (CFX). At identical dosage regime High Performance Liquid Chromatograhy (HPLC) residues of EFX were 6-fold greater than CFX ones. Maximun concentrations were detected at the second day after the administration withdrawal. The limits of detection were 0.019 mu g/g for EFX and 0.156 mu g/g for CFX. The recovery was 36-50% for CFX and 49-85% for EFX. The withdrawal treatment periods in hens are six days for EFX and five days for CFX in order to avoid violative levels of egg residues. (C) 1997 Elsevier Science B.V.

引用

页码：253 / 256

页数：4