The use of supercritical fluid extraction for the determination of amphetamines in hair

被引：30

作者：

Allen, DL ^{[1
]}

Oliver, JS ^{[1
]}

机构：

[1] Univ Glasgow, Dept Forens Med & Sci, Glasgow G12 8QQ, Lanark, Scotland

来源：

FORENSIC SCIENCE INTERNATIONAL | 2000年 / 107卷 / 1-3期

关键词：

hair analysis; supercritical fluid extraction; methylenedioxyamphetamine; methylenedioxyethylamphetamine; methylenedioxymethamphetamine;

D O I：

10.1016/S0379-0738(99)00163-2

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A laboratory study interested in the analysis of human hair for drugs-of-abuse was conducted to determine if drugs could be detected and quantified from hair. Supercritical fluid extraction (SFE) techniques followed by GC-MS analysis were applied to extract amphetamines from hair. The group of amphetamines included methylenedioxyamphetamine (MDA), methylenedioxymetamphetamine (MDMA), methylenedioxyethylamphetamine (MDEA) and internal standard mephentermine (MP). To validate information on amphetamine use in hair, powdered hair samples free from drugs were collected and soaked in a known amphetamine standard solution. Authentic fortified case hair samples taken from known drug users known to have consumed amphetamines were also analyzed for amphetamine. Results from this study show that amphetamine use can be detected in spiked and authentic fortified human hair using SFE techniques for qualitative and quantitative reproducible results. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：191 / 199

页数：9

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