Deposition and properties of polyelectrolyte multilayers studied by ATR-FTIR spectroscopy

被引：51

作者：

Müller, M

Brissová, M

Rieser, T

Powers, AC

Lunkwitz, K

机构：

[1] Inst Polymerforsch Dresden, D-01069 Dresden, Germany

[2] Vanderbilt Univ, Dept Med, Nashville, TN 37232 USA

来源：

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 1999年 / 8-9卷

基金：

美国国家卫生研究院;

关键词：

ATR-FTIR spectroscopy; polyelectrolyte multilayer assemblies; protein adsorption;

D O I：

10.1016/S0928-4931(99)00033-8

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In-situ ATR-FTIR spectroscopy was adopted to study multilayer assemblies of oppositely charged polyelectrolytes consecutively deposited on plasma treated SiO surface. Two different polyelectrolyte systems were selected for this series of studies in order to address (i) conformational changes in polyelectrolyte multilayers as a response to the external stimuli and (ii) protein adsorption on preformed polyelectrolyte multilayers. The former phenomenon was examined for the polyelectrolyte pair of poly(acrylic acid) (PAA) and poly(L-lysine) (PLL), where PLL provides an advantage of detecting the early adsorption events due to its intense amide I band. Protein adsorption was followed on the multilayer assembly consisting of sodium alginate (SA), cellulose sulfate (CS) and poly(methylene-coguanidine) (PMCG). These multilayers were used as a model system to simulate protein interactions with the membranes formed by polyelectrolyte complexation. (C) 1999 Elsevier Science S.A. All rights reserved.

引用

页码：163 / 169

页数：7

共 30 条

[1] CONFORMATIONAL-CHANGES IN ADSORBED PROTEINS [J].