Steroid signaling and temperature-dependent sex determination - Reviewing the evidence for early action of estrogen during ovarian determination in turtles

被引：83

作者：

Ramsey, Mary ^{[1
]}

Crews, David ^{[1
]}

机构：

[1] Univ Texas Austin, Sect Integrat Biol, Austin, TX 78712 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2009年 / 20卷 / 03期

关键词：

Temperature-dependent sex determination; Trachemys scripta; Estrogen; Aromatase; Ovary; EARED SLIDER TURTLE; SEXUALLY DIMORPHIC EXPRESSION; APALONE-MUTICA TURTLES; ADRENAL-KIDNEY-GONAD; ALPHA ER-ALPHA; TRACHEMYS-SCRIPTA; GENE-EXPRESSION; RECEPTOR-BETA; AROMATASE EXPRESSION; FACTOR-I;

D O I：

10.1016/j.semcdb.2008.10.004

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The developmental processes underlying gonadal differentiation are conserved across vertebrates, but the triggers initiating these trajectories are extremely variable. The red-eared slider turtle (Trachemys scripta elegans) exhibits temperature-dependent sex determination (TSD), a system where incubation temperature during a temperature-sensitive period of development determines offspring sex. However, gonadal sex is sensitive to both temperature and hormones during this period-particularly estrogen. We present a model for temperature-based differences in aromatase expression as a critical step in ovarian determination. Localized estrogen production facilitates ovarian development while inhibiting male-specific gene expression. At male-producing temperatures aromatase is not upregulated, thereby allowing testis development. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：283 / 292

页数：10

共 120 条

[31] Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II [J].

Fan, WuQiang ;

Yanase, Toshihiko ;

Morinaga, Hidetaka ;

Gondo, Shigeki ;

Okabe, Taijiro ;

Nomura, Masatoshi ;

Hayes, Tyrone B. ;

Takayanagi, Ryolchi ;

Nawata, Hajime .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 355 (04) :1012-1018

[32] LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis [J].

Fayard, E ;

Auwerx, J ;

Schoonjans, K .

TRENDS IN CELL BIOLOGY, 2004, 14 (05) :250-260

[33]

FERGUSON MWJ, 1983, J ZOOL, V200, P143

[34] Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene [J].

Fisher, CR ;

Graves, KH ;

Parlow, AF ;

Simpson, ER .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) :6965-6970

[35] Expression of estrogen receptor-β protein in rodent ovary [J].

Fitzpatrick, SL ;

Funkhouser, JM ;

Sindoni, DM ;

Stevis, PE ;

Deecher, DC ;

Bapat, AR ;

Merchenthaler, I ;

Frail, DE .

ENDOCRINOLOGY, 1999, 140 (06) :2581-2591

[36] Developmental expression of steroidogenic factor 1 in a turtle with temperature-dependent sex determination [J].

Fleming, A ;

Wibbels, T ;

Skipper, JK ;

Crews, D .

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1999, 116 (03) :336-346

[37] Estradiol and incubation temperature modulate regulation of steroidogenic factor 1 in the developing gonad of the red-eared slider turtle [J].

Fleming, A ;

Crews, D .

ENDOCRINOLOGY, 2001, 142 (04) :1403-1411

[38] Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: Insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype [J].

Frasor, J ;

Danes, JM ;

Komm, B ;

Chang, KCN ;

Lyttle, CR ;

Katzenellenbogen, BS .

ENDOCRINOLOGY, 2003, 144 (10) :4562-4574

[39] Long-term sex reversal by oestradiol in amniotes with heteromorphic sex chromosomes [J].

Freedberg, Steven ;

Bowden, Rachel M. ;

Ewert, Michael A. ;

Sengelaub, Dale R. ;

Nelson, Craig E. .

BIOLOGY LETTERS, 2006, 2 (03) :378-381

[40] Alligator aromatase cDNA sequence and its expression in embryos at male and female incubation temperatures [J].

Gabriel, WN ;

Blumberg, B ;

Sutton, S ;

Place, AR ;

Lance, VA .

JOURNAL OF EXPERIMENTAL ZOOLOGY, 2001, 290 (05) :439-448

← 1 2 3 4 5 6 7 8 9 10 →