Oncological problems in pancreatic cancer surgery

被引:56
作者
Nakao, Akimasa [1 ]
Fujii, Tsutomu [1 ]
Sugimoto, Hiroyuki [1 ]
Kanazumi, Naohito [1 ]
Nomoto, Shuji [1 ]
Kodera, Yasuhiro [1 ]
Inoue, Soichiro [1 ]
Takeda, Shin [1 ]
机构
[1] Nagoya Univ, Grad Sch Med, Dept Surg 2, Showa Ku, Nagoya, Aichi 4668550, Japan
关键词
pancreatic cancer; extended resection; molecular diagnosis; micrometastasis; adjuvant therapy;
D O I
10.3748/wjg.v12.i28.4466
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Despite the development of more sophisticated diagnostic techniques, pancreatic carcinoma has not yet been detected in the early stage. Surgical resection provides the only chance for cure or long-term survival. The resection rate has increased due to recent advances in surgical techniques and the application of extensive surgery. However, the postoperative prognosis has been poor due to commonly occurring liver metastasis, local recurrence and peritoneal dissemination. Recent molecular-biological studies have clarified occult metastasis, micrometastasis and systemic disease in pancreatic cancer. Several oncological problems in pancreatic cancer surgery are discussed in the present review. (C) 2006 The WJG Press. All rights reserved.
引用
收藏
页码:4466 / 4472
页数:7
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