How oxygen makes its presence felt

被引：129

作者：

Kaelin, WG

机构：

[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Howard Hughes Med Inst, Boston, MA 02115 USA

[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA

来源：

GENES & DEVELOPMENT | 2002年 / 16卷 / 12期

关键词：

D O I：

10.1101/gad.1003602

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

[No abstract available]

引用

页码：1441 / 1445

页数：5

共 41 条

[21] Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch [J].

Lando, D ;

Peet, DJ ;

Whelan, DA ;

Gorman, JJ ;

Whitelaw, ML .

SCIENCE, 2002, 295 (5556) :858-861

[22] Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoma [J].

Lavaissiere, L ;

Jia, S ;

Nishiyama, M ;

delaMonte, S ;

Stern, AM ;

Wands, JR ;

Friedman, PA .

JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (06) :1313-1323

[23] FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity [J].

Mahon, PC ;

Hirota, K ;

Semenza, GL .

GENES & DEVELOPMENT, 2001, 15 (20) :2675-2686

[24] THE 2-OXOGLUTARATE BINDING-SITE OF PROLYL 4-HYDROXYLASE - IDENTIFICATION OF DISTINCT SUBSITES AND EVIDENCE FOR 2-OXOGLUTARATE DECARBOXYLATION IN A LIGAND REACTION AT THE ENZYME-BOUND FERROUS ION [J].

MAJAMAA, K ;

HANAUSKEABEL, HM ;

GUNZLER, V ;

KIVIRIKKO, KI .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1984, 138 (02) :239-245

[25] The contribution of VHL substrate binding and HIF1-α to the phenotype of VHL loss in renal cell carcinoma [J].

Maranchie, JK ;

Vasselli, JR ;

Riss, J ;

Bonifacino, JS ;

Linehan, WM ;

Klausner, RD .

CANCER CELL, 2002, 1 (03) :247-255

[26] Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation [J].

Masson, N ;

Willam, C ;

Maxwell, PH ;

Pugh, CW ;

Ratcliffe, PJ .

EMBO JOURNAL, 2001, 20 (18) :5197-5206

[27] The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis [J].

Maxwell, PH ;

Wiesener, MS ;

Chang, GW ;

Clifford, SC ;

Vaux, EC ;

Cockman, ME ;

Wykoff, CC ;

Pugh, CW ;

Maher, ER ;

Ratcliffe, PJ .

NATURE, 1999, 399 (6733) :271-275

[28]

MIN JH, 2002, IN PRESS SCIENCE

[29] Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction [J].

Nwogu, JI ;

Geenen, D ;

Bean, M ;

Brenner, MC ;

Huang, XF ;

Buttrick, PM .

CIRCULATION, 2001, 104 (18) :2216-2221

[30] OCCURRENCE OF BETA-HYDROXYLATED ASPARAGINE RESIDUES IN NON-VITAMIN-K-DEPENDENT PROTEINS CONTAINING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS [J].

PRZYSIECKI, CT ;

STAGGERS, JE ;

RAMJIT, HG ;

MUSSON, DG ;

STERN, AM ;

BENNETT, CD ;

FRIEDMAN, PA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (22) :7856-7860

← 1 2 3 4 5 →