Developments in the clinical understanding of osteoarthritis

被引:202
作者
Felson, David T. [1 ]
机构
[1] Boston Univ, Sch Med, Boston, MA 02118 USA
关键词
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; BONE-MARROW LESIONS; RANDOMIZED CONTROLLED-TRIAL; CHRONIC KNEE PAIN; CARTILAGE LOSS; HIP OSTEOARTHRITIS; JOINT SPACE; HAND OSTEOARTHRITIS; RADIOGRAPHIC PROGRESSION; DISEASE PROGRESSION;
D O I
10.1186/ar2531
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
With the recognition that osteoarthritis is a disease of the whole joint, attention has focused increasingly on features in the joint environment which cause ongoing joint damage and are likely sources of pain. This article reviews current ways of assessing osteoarthritis progression and what factors potentiate it, structural abnormalities that probably produce pain, new understandings of the genetics of osteoarthritis, and evaluations of new and old treatments.
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页数:11
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