Synthesis of porous iron oxide microspheres by a double hydrophilic block copolymer

被引：17

作者：

Bastakoti, B. P. ^{[1
]}

Sukegawa, Hiroaki ^{[1
]}

Wu, Kevin C. -W. ^{[2
]}

Yamauchi, Yusuke ^{[1
]}

机构：

[1] Natl Inst Mat Sci, Tsukuba, Ibaraki 3050044, Japan

[2] Natl Taiwan Univ, Dept Chem Engn, Taipei 10617, Taiwan

来源：

RSC ADVANCES | 2014年 / 4卷 / 20期

关键词：

POLY(ACRYLIC ACID); NANOPARTICLES; TEMPLATE; TOXICITY; DESIGN;

D O I：

10.1039/c3ra47490a

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Porous microspheres of iron oxide (Fe2O3) are synthesized using a double hydrophilic block copolymer of poly(ethylene oxide)-block-poly(acrylic acid) (PEO-b-PAA). The PAA block with negative charge strongly interacts with ferric ions. The assembly of primary nanoparticles at elevated temperature forms the porous microsphere of Fe2O3. The MTT assay of the microspheres based on HepG2 cell indicates good biocompatibility. The thorough porosity of microspheres can accommodate a large amount of anticancer drug cisplatin.

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收藏

页码：9986 / 9989

页数：4

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