Predictors of 1-year survival assessed at the time of bone marrow transplantation

被引:28
作者
Chang, G
Orav, EJ
Tong, MY
Antin, JH
机构
[1] Brigham & Womens Hosp, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Dept Med Biostat, Boston, MA 02115 USA
[5] Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
D O I
10.1176/appi.psy.45.5.378
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The purpose of this prospective cohort study was to identify pretransplant and transplant predictors of 1-year survival after allogeneic hematopoietic stem cell transplantation (HSCT) for chronic myelogenous leukemia. Psychosocial and behavioral variables such as alcohol abuse and cigarette smoking were systematically assessed at the time of HSCT with structured diagnostic instruments. A total of 114 patients participated, with an overall 1-year survival rate of 66%. Lifetime alcohol and other substance use, cigarette smoking, depression, and quality of life prior to transplant were not found to affect 1-year survival. However, other clinical variables prior to transplant and once transplant occurred were found to predict survival.
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页码:378 / 385
页数:8
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