In vitro activities of dalbavancin and 12 other agents against 329 aerobic and anaerobic gram-positive isolates recovered from diabetic foot infections

被引：49

作者：

Goldstein, Ellie J. C.

Citron, Diane M.

Warren, Yumi A.

Tyrrell, Kerin L.

Merriam, C. Vreni

Fernandez, Helen T.

机构：

[1] RM Alden Res Lab, Santa Monica, CA 90404 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90073 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 08期

关键词：

D O I：

10.1128/AAC.00286-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Tests of dalbavancin's in vitro activity against 209 aerobic and 120 anaerobic isolates from pretreatment diabetic foot infections showed an MIC90 of <= 0.125 mu g/ml against methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), and 120 anaerobes (Clostridium perfringens, other clostridia, Peptoniphilus asaccharolyticus, Finegoldia magna, and Anaerococcus prevotii), compared to respective MIC(90)s for MSSA and MRSA of 0.5 and 1 mu g/ml for vancomycin, 4 and 4 mu g/ml for linezolid, 0.5 and 0.5 mu g/ml for daptomycin, and 0.25 and > 8 mu g/ml for clindamycin.

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收藏

页码：2875 / 2879

页数：5

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