Ancistrocongolines A-D, new naphthylisoquinoline alkaloids from Ancistrocladus congolensis

被引：47

作者：

Bringmann, G ^{[1
]}

Messer, K

Brun, R

Mudogo, V

机构：

[1] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

[2] Schweizer Trop Inst, CH-4002 Basel, Switzerland

[3] Univ Kinshasa, Fac Sci, Kinshasa, DEM REP CONGO

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 08期

关键词：

D O I：

10.1021/np010622d

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new naphthylisoquinoline alkaloids ancistrocongolines A-D (4-7) were isolated from Ancistrocladus congolensis, along with the known compound korupensamine A (8) Structural elucidation was achieved by chemical, spectroscopic, and chiroptical methods Their biological activities against the pathogens of malaria, Leishmaniasis, Chagas disease, and African sleeping sickness were evaluated.

引用

页码：1096 / 1101

页数：6

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