FISH-mapping of LEP and SLC26A2 genes in sheep, goat and cattle R-banded chromosomes:: comparison between bovine, ovine and caprine chromosome 4 (BTA4/OAR4/CHI4) and human chromosome 7 (HSA7)

被引：11

作者：

Perucatti, A.

Di Meo, G. P.

Vallinoto, M.

Kierstein, G.

Schneider, M. P. C.

Incarnato, D.

Jambrenghi, A. Caputi

Mohammadi, G.

Vonghia, G.

Silva, A.

Brenig, B.

Iannuzzi, L.

机构：

[1] CNR, ISPAAM, Lab Anim Cytogenet & Gene Mapping, I-80147 Naples, Italy

[2] Fed Univ Para, Lab Genet & Biol Mol, BR-66059 Belem, Para, Brazil

[3] Univ Gottingen, Inst Vet Med, D-3400 Gottingen, Germany

[4] Fed Univ Para, Lab Polimorfismo DNA, BR-66059 Belem, Para, Brazil

[5] Univ Bari, Dept Anim Prod, Fac Agr Sci, Bari, Italy

[6] Shahid Chamran Univ, Fac Vet, Clin Sci Grp, Ahvaz, Iran

来源：

CYTOGENETIC AND GENOME RESEARCH | 2006年 / 115卷 / 01期

关键词：

D O I：

10.1159/000094794

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Sheep (OAR), goat (CHI) and cattle (BTA) R-banded chromosome preparations, obtained from synchronized cell cultures, were used to FISH-map leptin (LEP) and solute carrier family 26 member 2 (SLC26A2) genes on single chromosome bands. LEP maps on OAR4q32 and CH14q32, being the first assignment of this gene to these two species. SLC26A2 maps on BTA7q24, OAR5q24 and CH17q24. This gene, too, was assigned for the fist time to both sheep and goat chromosomes, while it was more precisely localized on a single chromosome band in cattle. Improved cytogenetic maps of BTA4/OAR4/CH14 were constructed and compared with HSA7 revealing five main conserved segments and complex chromosome rearrangements, including a centromere repositioning, differentiating HSA7 and BTA4/OAR4/CH14.

引用

页码：7 / 9

页数：3

共 17 条

[1] Molecular cloning, mapping, and functional analysis of the bovine sulfate transporter SLC26a2 gene [J].