Efficient synthesis of a porphyrin-N-tripod conjugate with covalently linked proximal ligand:: Toward new-generation active-site models of cytochrome c oxidase

被引：19

作者：

Collman, JP ^{[1
]}

Zhong, M

Wang, Z

Rapta, M

Rose, E

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

[2] CNRS, Lab Synthese Organ & Organomet, UMR 7611, F-75252 Paris 05, France

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 13期

关键词：

D O I：

10.1021/ol9911730

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new generation cytochrome c oxidase active-site model compound (4) featuring both a trisimidazolyl moiety and a proximal base has been designed and efficiently synthesized. During this study, a facile method based on the chemistry of a 4 magnesioimidazole derivative to synthesize 4-imidazolyl-containing tripodal ligands (7) has been developed.

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收藏

页码：2121 / 2124

页数：4

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