A mutation in the luxS gene influences Listeria monocytogenes biofilm formation

被引：89

作者：

Sela, Shlomo ^{[1
]}

Frank, Shmulik

Belausov, Eddy

Pinto, Riky

机构：

[1] Agr Res Org, Volcani Ctr, Dept Food Sci,Inst Technol & Storage Fresh Produc, Microbial Food Safety Res Unit, IL-50250 Bet Dagan, Israel

[2] Agr Res Org, Volcani Ctr, Confocal Microscopy Unit, IL-50250 Bet Dagan, Israel

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2006年 / 72卷 / 08期

关键词：

D O I：

10.1128/AEM.00048-06

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Using a Vibrio harveyi reporter strain, we demonstrated that Listeria monocytogenes secretes a functional autoinducer 2 (AI-2)-like signal. A luxS-deficient mutant produced a denser biofilm and attached to a glass surface 19-fold better than the parent strain. Exogenous AI-2 failed to restore the wild-type phenotype to the mutant. It seems that an intact luxS gene is associated with repression of components required for attachment and biofilm formation.

引用

页码：5653 / 5658

页数：6

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