Phenanthridinium as an artificial base and charge donor in DNA

被引：51

作者：

Amann, N ^{[1
]}

Huber, R ^{[1
]}

Wagenknecht, HA ^{[1
]}

机构：

[1] Tech Univ Munich, Inst Organ Chem & Biochem, D-85747 Garching, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 14期

关键词：

DNA; electron transfer; ethidium ion; fluorescence spectroscopy; oligonucleotides;

D O I：

10.1002/anie.200353153

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A tool for time-resolved studies: The phenanthridinium unit of ethidium was incorporated into oligonucleotides (see scheme) as an artificial DNA base. The resulting duplexes can be used to study electron-transfer processes by spectroscopic techniques and to compare the rates of reductive electron transfer and oxidative hole transfer.

引用

页码：1845 / 1847

页数：3

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