Flow cytometry tear analysis in patients with chronic allergic conjunctivitis

被引：8

作者：

Avunduk, AM

Avunduk, MC

Dayioglu, YS

Centinkaya, K

机构：

[1] BLACK SEA TECH UNIV,SCH MED,DEPT OPHTHALMOL,TRABZON,TURKEY

[2] ANKARA ONCOL HOSP,DEPT PATHOL,ANKARA,TURKEY

来源：

JAPANESE JOURNAL OF OPHTHALMOLOGY | 1997年 / 41卷 / 02期

关键词：

activated B lymphocyte; allergy; chronic allergic conjunctivitis; flow cytometry; human tears; T helper lymphocyte; T lymphocyte;

D O I：

10.1016/S0021-5155(97)00012-9

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Tears from patients with chronic allergic conjunctivitis were analyzed with flow cytometry to determine the function of the T lymphocyte-related immunological reactions in the disease pathogenesis. Twenty-eight patients and 22 normal volunteers were studied; tears were obtained with capillary tubes. T helper/T suppressor ratios and the percentages of HLA DR+, CD23+, and CD3+ cells were significantly higher in patients than in controls. This study provides support for the hypothesis that chronic allergic conjunctivitis results from T lymphocyte-related immunological reactions. (C) 1997 Japanese Ophthalmological Society.

引用

页码：67 / 70

页数：4

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