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T-CELLS AND EOSINOPHILS IN THE PATHOGENESIS OF ASTHMA

被引：537
作者：
CORRIGAN, CJ
KAY, AB
机构：
[1] C.J. Corrigan and A.B. Kay are, the Dept of Allergy and Clinical Immunology, National Heart and Lung Institute, London, SW3 6LY, Dovehouse Street
来源：
IMMUNOLOGY TODAY | 1992年 / 13卷 / 12期
关键词：
D O I：
10.1016/0167-5699(92)90026-4
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Persistent asthma is characterized by chronic inflammation of the bronchial mucosa, where T cells and eosinophils are prominent. This article summarizes the evidence that asthmatic bronchial inflammation is initiated and propagated by cytokines secreted by activated T cells and other cells, and describes how the release of specific cytokines could result in local preferential accumulation and activation of eosinophils.
引用
收藏
页码：501 / 507
页数：7
相关论文
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