Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas

被引:170
作者
Pallud, Johan
Mandonnet, Emmanuel
Duffau, Hugues
Kujas, Michele
Guillevin, Remy
Galanaud, Damien
Taillandier, Luc
Capelle, Laurent
机构
[1] Hop La Pitie Salpetriere, Dept Neurosurg, Serv Neurochirurg, F-75651 Paris 13, France
[2] INSERM, U678, Paris, France
[3] Hop La Pitie Salpetriere, Serv Neuropathol, Paris, France
[4] Hop La Pitie Salpetriere, Serv Neuroradiol, Paris, France
[5] CHU Nancy, Serv Neurol, Nancy, France
关键词
D O I
10.1002/ana.20946
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A consecutive series of 143 unselected adult patients with histologically proved World Health Organization grade II gliomas was reviewed to assess the prognostic value of growth rates of mean tumor diameters on successive magnetic resonance images before treatment. There is an inverse correlation between growth rates and survival (p < 0.001; median survival at 5.16 years for a growth rate of 8mm/year or more; median survival > 15.0 years for a growth rate < 8mm/year). Thus, individual magnetic resonance imaging tumor growth rates should be incorporated in the planning of the initial therapeutic strategy of grade II gliomas.
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页码:380 / 383
页数:4
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