Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas

被引：170

作者：

Pallud, Johan

Mandonnet, Emmanuel

Duffau, Hugues

Kujas, Michele

Guillevin, Remy

Galanaud, Damien

Taillandier, Luc

Capelle, Laurent

机构：

[1] Hop La Pitie Salpetriere, Dept Neurosurg, Serv Neurochirurg, F-75651 Paris 13, France

[2] INSERM, U678, Paris, France

[3] Hop La Pitie Salpetriere, Serv Neuropathol, Paris, France

[4] Hop La Pitie Salpetriere, Serv Neuroradiol, Paris, France

[5] CHU Nancy, Serv Neurol, Nancy, France

来源：

ANNALS OF NEUROLOGY | 2006年 / 60卷 / 03期

关键词：

D O I：

10.1002/ana.20946

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A consecutive series of 143 unselected adult patients with histologically proved World Health Organization grade II gliomas was reviewed to assess the prognostic value of growth rates of mean tumor diameters on successive magnetic resonance images before treatment. There is an inverse correlation between growth rates and survival (p < 0.001; median survival at 5.16 years for a growth rate of 8mm/year or more; median survival > 15.0 years for a growth rate < 8mm/year). Thus, individual magnetic resonance imaging tumor growth rates should be incorporated in the planning of the initial therapeutic strategy of grade II gliomas.

引用

页码：380 / 383

页数：4

共 21 条

[11]

KLEIHUES P, 2000, TUMORS NERVOUS SYSTE

[12] Supratentorial low-grade glioma in adults: An analysis of prognostic factors and timing of radiation [J].