Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials

被引：640

作者：

Newlands, ES

Stevens, MFG

Wedge, SR

Wheelhouse, RT

Brock, C

机构：

[1] UNIV NOTTINGHAM,DEPT PHARMACEUT SCI,CANC RES CAMPAIGN,EXPT CANC CHEMOTHERAPY RES GRP,NOTTINGHAM NG7 2RD,ENGLAND

[2] UNIV TEXAS,COLL PHARM,DRUGS DYNAM INST,AUSTIN,TX 78712

来源：

CANCER TREATMENT REVIEWS | 1997年 / 23卷 / 01期

关键词：

D O I：

10.1016/S0305-7372(97)90019-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：35 / 61

页数：27

共 106 条

[51]

Liu L., 1996, Proceedings of the American Association for Cancer Research Annual Meeting, V37, P365

[52]

Liu LL, 1996, CANCER RES, V56, P1880

[53] ANTITUMOR IMIDAZOTETRAZINES .25. CRYSTAL-STRUCTURE OF 8-CARBAMOYL-3-METHYLIMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONE (TEMOZOLOMIDE) AND STRUCTURAL COMPARISONS WITH THE RELATED DRUGS MITOZOLOMIDE AND DTIC [J].

LOWE, PR ;

SANSOM, CE ;

SCHWALBE, CH ;

STEVENS, MFG ;

CLARK, AS .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (18) :3377-3382

[54] ANTITUMOR IMIDAZOTETRAZINES .14. SYNTHESIS AND ANTITUMOR-ACTIVITY OF 6-SUBSTITUTED AND 8-SUBSTITUTED IMIDAZO[5,1-D]-1,2,3,5-TETRAZINONES AND 8-SUBSTITUTED PYRAZOLO[5,1-D]-1,2,3,5-TETRAZINONES [J].

LUNT, E ;

NEWTON, CG ;

SMITH, C ;

STEVENS, GP ;

STEVENS, MFG ;

STRAW, CG ;

WALSH, RJA ;

WARREN, PJ ;

FIZAMES, C ;

LAVELLE, F ;

LANGDON, SP ;

VICKERS, LM .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (02) :357-366

[55]

MITCHELL RB, 1993, CANCER CHEMOTH PHARM, V32, P59

[56] MOLECULAR ANALYSIS OF O-6-SUBSTITUTED GUANINE-INDUCED MUTAGENESIS OF RAS ONCOGENES [J].

MITRA, G ;

PAULY, GT ;

KUMAR, R ;

PEI, GK ;

HUGHES, SH ;

MOSCHEL, RC ;

BARBACID, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (22) :8650-8654

[57] ALTERATION OF DNA BY 5-(3-METHYL-1-TRIAZENO)IMIDAZOLE-4-CARBOXAMIDE (NSC-407347) [J].

MIZUNO, NS ;

DECKER, RW .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (23) :2643-2647

[58]

NEIJT JP, 1987, P ECCO4 4 EUR C CLIN, V214

[59] The Charing Cross Hospital experience with temozolomide in patients with gliomas [J].

Newlands, ES ;

OReilly, SM ;

Glaser, MG ;

Bower, M ;

Evans, H ;

Brock, C ;

Brampton, MH ;

Colquhoun, I ;

Lewis, P ;

RiceEdwards, JM ;

Illingworth, RD ;

Richards, PG .

EUROPEAN JOURNAL OF CANCER, 1996, 32A (13) :2236-2241

[60] ANTITUMOR IMIDAZOTETRAZINES .26. PHASE-I TRIAL OF TEMOZOLOMIDE (CCRG-81045, M-AND-B 39831, NSC-362856) [J].

NEWLANDS, ES ;

BLACKLEDGE, GRP ;

SLACK, JA ;

RUSTIN, GJS ;

SMITH, DB ;

STUART, NSA ;

QUARTERMAN, CP ;

HOFFMAN, R ;

STEVENS, MFG ;

BRAMPTON, MH ;

GIBSON, AC .

BRITISH JOURNAL OF CANCER, 1992, 65 (02) :287-291

← 1 2 3 4 5 6 7 8 9 10 →