Fluorination of Boronic Acids Mediated by Silver(I) Triflate

被引：227

作者：

Furuya, Takeru ^{[1
]}

Ritter, Tobias ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 13期

关键词：

REDUCTIVE ELIMINATION; CATALYZED BORYLATION; ARYL; DERIVATIVES; REACTIVITY; CHEMISTRY; ALCOHOLS; AMIDES;

D O I：

10.1021/ol901113t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A regiospecific Ag-mediated fluorination reaction of aryl- and alkenylboronic acids and esters is reported. The fluorination reaction uses commercially available reagents, does not require the addition of exogenous ligands, and can be performed on a multigram scale. This report discloses the first practical reaction sequence from arylboronic acid to aryl fluorides.

引用

页码：2860 / 2863

页数：4

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