Swallowing dynein: a missing link in RNA localization?

被引:15
作者
Hays, T
Karess, R
机构
[1] Univ Minnesota, Dept Genet Cell & Dev Biol, Minneapolis, MN 55455 USA
[2] CNRS, Ctr Genet Mol, F-91198 Gif Sur Yvette, France
关键词
D O I
10.1038/35008687
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Localization of bicoid messenger RNA to the anterior cortex of the developing oocyte is essential for correct anterior-posterior patterning of the Drosophila embryo. It now seems that, the Swallow protein functions as an adaptor, bridging bicoid mRNA to dynein, a molecular motor that would transport the complex anteriorly along microtubules.
引用
收藏
页码:E60 / E62
页数:3
相关论文
共 14 条
[11]  
STJOHNSTON D, 1995, CELL, V81, P167
[12]  
THEURKAUF WE, 1992, DEVELOPMENT, V115, P923
[13]   Isolation of a ribonucleoprotein complex involved in mRNA localization in Drosophila oocytes [J].
Wilhelm, JE ;
Mansfield, J ;
Hom-Booher, N ;
Wang, SX ;
Turck, CW ;
Hazelrigg, T ;
Vale, RD .
JOURNAL OF CELL BIOLOGY, 2000, 148 (03) :427-439
[14]  
WILLHELM JE, 1993, J CELL BIOL, V123, P269