Novel microreactors for functional polymer beads

被引:289
作者
Nisisako, T [1 ]
Torii, T [1 ]
Higuchi, T [1 ]
机构
[1] Univ Tokyo, Grad Sch Engn, Dept Precis Engn, Bunkyo Ku, Tokyo 1138656, Japan
关键词
microfluidics; droplet formation; bicolored polymeric microspheres; monodisperse emulsion;
D O I
10.1016/j.cej.2003.11.019
中图分类号
X [环境科学、安全科学];
学科分类号
08 [工学]; 0830 [环境科学与工程];
摘要
A novel technique is described for preparing multiple polymeric microspheres of the same size. A monodisperse droplet suspension of an acrylic monomer was prepared in a T-shaped microchannel, and particles of accurately the same size were produced by subsequent polymerization. The droplet/particle size was varied flexibly in the range of diameters 30-120 mum by changing the flow conditions in a microfluidic device. The resulting products have a coefficient of variation (CV) below 2%. A diagram of the flow parameters showed a clear region in which monosized drops were formed successfully. Furthermore, using another microfluidic device, hemi spherically colored acrylic microspheres of 90-190 mum in diameter were engineered with a coefficient of variation of less than 1%. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:23 / 29
页数:7
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