Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum

被引：72

作者：

Giacchino, Mareva

Chiapello, Nadia

Bezzio, Stefania

Fagioli, Franca

Saracco, Paola

Alfarano, Alda

Martini, Vincenza

Cimino, Giuseppe

Martino, Pietro

Girmenia, Corrado

机构：

[1] Univ Roma La Sapienza, Dipartimento Biotecnol Cellulari & Ematol, I-00161 Rome, Italy

[2] Univ Turin, Dipartimento Sci Pediat & Adolescenza, Turin, Italy

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2006年 / 44卷 / 09期

关键词：

D O I：

10.1128/JCM.00856-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We report three cases of invasive Geotrichum capitatum infection in patients with acute leukemia for which an enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Supernatants obtained from suspensions of 17 G. capitatum strains gave positive reactions with the Aspergillus galactomannan ELISA. These clinical and laboratory data seem. to suggest that G. capitatum produces a soluble antigen that is cross-reactive with Aspergillus galactomannan.

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页码：3432 / 3434

页数：3

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