Using pharmacogenetics to improve drug safety and efficacy

被引：38

作者：

Haga, SB

Burke, W

机构：

[1] Univ Washington, Dept Med Hist & Eth, Seattle, WA 98195 USA

[2] Ctr Advancement Gen, Rockville, MD USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2004年 / 291卷 / 23期

关键词：

D O I：

10.1001/jama.291.23.2869

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2869 / 2871

页数：3

共 28 条

[11] An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions [J].

Khoury, MJ ;

Yang, QH ;

Gwinn, M ;

Little, JL ;

Flanders, WD .

GENETICS IN MEDICINE, 2004, 6 (01) :38-47

[12] Pharmacogenetics as a molecular basis for individualized drug therapy: The thiopurine S-methyltransferase paradigm [J].

Krynetski, EY ;

Evans, WE .

PHARMACEUTICAL RESEARCH, 1999, 16 (03) :342-349

[13] A SINGLE-POINT MUTATION LEADING TO LOSS OF CATALYTIC ACTIVITY IN HUMAN THIOPURINE S-METHYLTRANSFERASE [J].

KRYNETSKI, EY ;

SCHUETZ, JD ;

GALPIN, AJ ;

PUI, CH ;

RELLING, MV ;

EVANS, WE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (04) :949-953

[14] Incidence of adverse drug reactions in hospitalized patients - A meta-analysis of prospective studies [J].

Lazarou, J ;

Pomeranz, BH ;

Corey, PN .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (15) :1200-1205

[15] Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism [J].

Lennard, L ;

Lilleyman, JS .

THERAPEUTIC DRUG MONITORING, 1996, 18 (04) :328-334

[16] Pharmacogenetics and pharmacogenomics in drug discovery and development: An overview [J].

Lindpaintner, K .

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2003, 41 (04) :398-410

[17] Genetic profiling versus drug rotation in the optimisation of anti hypertensive treatment [J].

Mackenzie, IS ;

Brown, MJ .

CLINICAL MEDICINE, 2002, 2 (05) :465-473

[18]

*NAT I GEN MED SCI, PHARM RES NETW

[19]

*NIH, NIH ROADM ACC MED DI

[20] Pharmacogenetics of drug metabolising enzymes: Importance for personalised medicine [J].

Oscarson, M .

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2003, 41 (04) :573-580

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