Fluoroquinolone-resistant Streptococcus pneumoniae strains occur frequently in elderly patients in Japan

被引：35

作者：

Yokota, S

Sato, K

Kuwahara, O

Habadera, S

Tsukamoto, N

Ohuchi, H

Akizawa, H

Himi, T

Fujii, N

机构：

[1] Sapporo Med Univ, Sch Med, Dept Microbiol, Chuo Ku, Sapporo, Hokkaido 0608556, Japan

[2] Sapporo Med Univ, Sch Med, Dept Otolaryngol, Chuo Ku, Sapporo, Hokkaido 0608556, Japan

[3] Wako Junyaku Co Ltd, Kita Ku, Sapporo, Hokkaido 0010015, Japan

[4] Sapporo Clin Lab Inc, Chuo Ku, Sapporo, Hokkaido 0600005, Japan

[5] SRL Hokkaido Inc, Chuo Ku, Sapporo, Hokkaido 0640919, Japan

[6] Hokkaido Univ, Hosp Med, Lab Med, Kita Ku, Sapporo, Hokkaido 0608648, Japan

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 10期

关键词：

D O I：

10.1128/AAC.46.10.3311-3315.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We identified and genetically characterized seven fluoroquinolone-resistant Streptococcus pneumoniae strains among 293 clinical strains isolated from 1999 to 2001 in Japan. The resistant strains were isolated only from adults, and 7 of 31 isolates (22.6%) were from patients more than 20 years old. Resistant strains were not found in 262 isolates from children under age 10.

引用

页码：3311 / 3315

页数：5

共 27 条

[21] Contribution of topoisomerase IV and DNA gyrase mutations in Streptococcus pneumoniae to resistance to novel fluoroquinolones [J].