Stereoselective formation of 1,2-diiodoalkenes and their application in the stereoselective synthesis of highly functionalised alkenes via Suzuki and Stille coupling reactions

被引：31

作者：

Hénaff, N ^{[1
]}

Whiting, A ^{[1
]}

机构：

[1] UMIST, Dept Chem, Manchester M60 1QD, Lancs, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2000年 / 03期

关键词：

D O I：

10.1039/a906832e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of an alkyne with iodine monochloride and sodium iodide at room temperature results in the formation of the thermodynamic (E)-diiodoalkene. The corresponding (Z)-diiodoalkene can also be produced, by treatment of the alkyne with iodine monochloride at -78 degrees C in the presence of tetraethylammonium iodide. Such 1,2-diiodoalkenes are useful for the synthesis of more functionalised alkenes by using either Stille or Suzuki cross-coupling protocols.

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页码：395 / 400

页数：6

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