In vitro inhibitory activity of boropinic acid against Helicobacter pylori

被引：25

作者：

Epifano, Francesco

Menghini, Luigi

Pagiotti, Rita

Angelini, Paola

Genovese, Salvatore

Curini, Massimo

机构：

[1] Dipartimento Sci Farm, I-66013 Chieti, CH, Italy

[2] Dipartimento Biol Vegetale & Biotecnol Agroambien, I-06126 Perugia, Italy

[3] Dipartimento Chim & Tecnol Farm, Sez Chim Organ, I-06123 Perugia, Italy

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 21期

关键词：

boropinic acid; Helicobacter pylori; prenyloxyphenylpropanoids;

D O I：

10.1016/j.bmcl.2006.08.043

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

In this study, we assessed in vitro minimum inhibitory concentration (MIC) values of some natural geranyloxycoumarins, geranyloxy- and isopentenyloxy acids against growth of Helicobacter pylori. Boropinic acid, active principle isolated from Boronia pinnata (Fam. Rutaceae), was seen to be the most effective compound with a MIC value of 1.62 mu g/mL. (c) 2006 Elsevier Ltd. All rights reserved.

引用

收藏

页码：5523 / 5525

页数：3

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