The sweet and bitter of mammalian taste

被引：64

作者：

Scott, K

机构：

[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Helen Wills Neurosci Inst, Berkeley, CA 94720 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2004年 / 14卷 / 04期

关键词：

D O I：

10.1016/j.conb.2004.06.003

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The discovery of two families of mammalian taste receptors has provided important insights into taste recognition and taste perception. Recent studies have examined the receptors and signaling pathways that mediate sweet, bitter, and amino acid taste detection in mammals. These studies demonstrate that taste cells are selectively tuned to different taste modalities and clarify the logic of taste coding in the periphery.

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页码：423 / 427

页数：5

相关论文

共 40 条

[1] A novel family of mammalian taste receptors [J].

Adler, E ;

Hoon, MA ;

Mueller, KL ;

Chandrashekar, J ;

Ryba, NJP ;

Zuker, CS .

CELL, 2000, 100 (06) :693-702

[2] Co-expression of calcium signaling components in vertebrate taste bud cells [J].

Asano-Miyoshi, M ;

Abe, K ;

Emori, Y .

NEUROSCIENCE LETTERS, 2000, 283 (01) :61-64

[3] IP3 receptor type 3 and PLCβ2 are co-expressed with taste receptors T1R and T2R in rat taste bud cells [J].

Asano-Miyoshi, M ;

Abe, K ;

Emori, Y .

CHEMICAL SENSES, 2001, 26 (03) :259-265

[4] Positional cloning of the mouse saccharin preference (Sac) locus [J].

Bachmanov, AA ;

Li, X ;

Reed, DR ;

Ohmen, JD ;

Li, SR ;

Chen, ZY ;

Tordoff, MG ;

de Jong, PJ ;

Wu, CY ;

West, DB ;

Chatterjee, A ;

Ross, DA ;

Beauchamp, GK .

CHEMICAL SENSES, 2001, 26 (07) :925-933

[5] The human TAS2R16 receptor mediates bitter taste in response to β-glucopyranosides [J].

Bufe, B ;

Hofmann, T ;

Krautwurst, D ;

Raguse, JD ;

Meyerhof, W .

NATURE GENETICS, 2002, 32 (03) :397-401

[6] CHROMOSOME MAPPING OF SOA, A GENE INFLUENCING GUSTATORY SENSITIVITY TO SUCROSE OCTAACETATE IN MICE [J].

CAPELESS, CG ;

WHITNEY, G ;

AZEN, EA .

BEHAVIOR GENETICS, 1992, 22 (06) :655-663

[7] T2Rs function as bitter taste receptors [J].

Chandrashekar, J ;

Mueller, KL ;

Hoon, MA ;

Adler, E ;

Feng, LX ;

Guo, W ;

Zuker, CS ;

Ryba, NJP .

CELL, 2000, 100 (06) :703-711

[8] Molecular and physiological evidence for glutamate (Umami) taste transduction via a G protein-coupled receptor [J].

Chaudhari, N ;

Roper, SD .

OLFACTION AND TASTE XII: AN INTERNATIONAL SYMPOSIUM, 1998, 855 :398-406

[9] A metabotropic glutamate receptor variant functions as a taste receptor [J].

Chaudhari, N ;

Landin, MA ;

Roper, SD .

NATURE NEUROSCIENCE, 2000, 3 (02) :113-119

[10]

Chaudhari N, 1996, J NEUROSCI, V16, P3817

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