Perspectives: Neurodegeneration - A glutamine-rich trail leads to transcription factors

被引:71
作者
Freiman, RN [1 ]
Tjian, R [1 ]
机构
[1] Univ Calif Berkeley, Howard Hughes Med Inst, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
关键词
D O I
10.1126/science.1073845
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
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页码:2149 / 2150
页数:3
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共 14 条
[1]   Transcriptional dysregulation in Huntington's disease [J].
Cha, JHJ .
TRENDS IN NEUROSCIENCES, 2000, 23 (09) :387-392
[2]   Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain [J].
DiFiglia, M ;
Sapp, E ;
Chase, KO ;
Davies, SW ;
Bates, GP ;
Vonsattel, JP ;
Aronin, N .
SCIENCE, 1997, 277 (5334) :1990-1993
[3]   Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease [J].
Dunah, AW ;
Jeong, H ;
Griffin, A ;
Kim, YM ;
Standaert, DG ;
Hersch, SM ;
Mouradian, MM ;
Young, AB ;
Tanese, N ;
Krainc, D .
SCIENCE, 2002, 296 (5576) :2238-2243
[4]   THE PROMOTER-SPECIFIC TRANSCRIPTION FACTOR-SP1 BINDS TO UPSTREAM SEQUENCES IN THE SV40 EARLY PROMOTER [J].
DYNAN, WS ;
TJIAN, R .
CELL, 1983, 35 (01) :79-87
[5]   Orchestrated response: a symphony of transcription factors for gene control [J].
Lemon, B ;
Tjian, R .
GENES & DEVELOPMENT, 2000, 14 (20) :2551-2569
[6]   Interaction of Huntington disease protein with transcriptional activator Sp1 [J].
Li, SH ;
Cheng, AL ;
Zhou, H ;
Lam, S ;
Rao, M ;
Li, H ;
Li, XJ .
MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (05) :1277-1287
[7]   A NOVEL GENE CONTAINING A TRINUCLEOTIDE REPEAT THAT IS EXPANDED AND UNSTABLE ON HUNTINGTONS-DISEASE CHROMOSOMES [J].
MACDONALD, ME ;
AMBROSE, CM ;
DUYAO, MP ;
MYERS, RH ;
LIN, C ;
SRINIDHI, L ;
BARNES, G ;
TAYLOR, SA ;
JAMES, M ;
GROOT, N ;
MACFARLANE, H ;
JENKINS, B ;
ANDERSON, MA ;
WEXLER, NS ;
GUSELLA, JF ;
BATES, GP ;
BAXENDALE, S ;
HUMMERICH, H ;
KIRBY, S ;
NORTH, M ;
YOUNGMAN, S ;
MOTT, R ;
ZEHETNER, G ;
SEDLACEK, Z ;
POUSTKA, A ;
FRISCHAUF, AM ;
LEHRACH, H ;
BUCKLER, AJ ;
CHURCH, D ;
DOUCETTESTAMM, L ;
ODONOVAN, MC ;
RIBARAMIREZ, L ;
SHAH, M ;
STANTON, VP ;
STROBEL, SA ;
DRATHS, KM ;
WALES, JL ;
DERVAN, P ;
HOUSMAN, DE ;
ALTHERR, M ;
SHIANG, R ;
THOMPSON, L ;
FIELDER, T ;
WASMUTH, JJ ;
TAGLE, D ;
VALDES, J ;
ELMER, L ;
ALLARD, M ;
CASTILLA, L ;
SWAROOP, M .
CELL, 1993, 72 (06) :971-983
[8]   Interference by Huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity [J].
Nucifora, FC ;
Sasaki, M ;
Peters, MF ;
Huang, H ;
Cooper, JK ;
Yamada, M ;
Takahashi, H ;
Tsuji, S ;
Troncoso, J ;
Dawson, VL ;
Dawson, TM ;
Ross, CA .
SCIENCE, 2001, 291 (5512) :2423-2428
[9]   Distinct subdomains of human TAFII130 are required for interactions with glutamine-rich transcriptional activators [J].
Saluja, D ;
Vassallo, MF ;
Tanese, N .
MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (10) :5734-5743
[10]   Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription [J].
Shimohata, T ;
Nakajima, T ;
Yamada, M ;
Uchida, C ;
Onodera, O ;
Naruse, S ;
Kimura, T ;
Koide, R ;
Nozaki, K ;
Sano, Y ;
Ishiguro, H ;
Sakoe, K ;
Ooshima, T ;
Sato, A ;
Ikeuchi, T ;
Oyake, M ;
Sato, T ;
Aoyagi, Y ;
Hozumi, I ;
Nagatsu, T ;
Takiyama, Y ;
Nishizawa, M ;
Goto, J ;
Kanazawa, I ;
Davidson, I ;
Tanese, N ;
Takahashi, H ;
Tsuji, S .
NATURE GENETICS, 2000, 26 (01) :29-36