Four new steroids from two octocorals

被引：44

作者：

Tomono, Y

Hirota, H

Imahara, Y

Fusetani, N ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Agr & Life Sci, Bunkyo Ku, Tokyo 1138657, Japan

[2] Natl Inst Fruit Tree Sci, Shimizu, Shizuoka 4240292, Japan

[3] RIKEN, Genom Sci Ctr, Wako, Saitama 3510198, Japan

[4] Wakayama Prefectural Museum Nat Hist, Wakayama 6420001, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 11期

关键词：

D O I：

10.1021/np990246l

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In search of analogues of isogosterones A-D (1-4), a group of antifouling 13,17-seco-steroids found in octocorals of the order Alcyonacea, we have isolated four new steroids possessing aromatic, enone, or dienone A-rings from two octocorals, Alcyonium gracillimum and Dendronephthya sp. These compounds, 3-methoxy-19-norpregna-1,3,5(10),20-tetraene (5), 3-(4-O-acetyl-6-deoxy-beta-galactopyranosyloxy)-19-norpregna-1,3,5(10),20-tetraene (6), 22,23-dihydroxycholesta-1,24-dien-3-one (7), and methyl 3-oxochola-4,-22-dien-24-oate (8), showed no antifouling activity against barnacle (Balanus amphitrite) larvae, but lethality to barnacle larvae at a concentration of 100 mu g/mL (LD100).

引用

页码：1538 / 1541

页数：4

共 25 条

[1] STEROIDAL ANTIFEEDANTS FROM THE DORID NUDIBRANCH ALDISA-SANGUINEA-COOPERI [J].