An experimental study on the behavior of wake flow behind a square cylinder in an upward gas-liquid vertical two-phase flow especially about the effects of blockage ratio of flow passage was examined. The results showed that Karman vortex is shed regularly under certain flow conditions for various Reynolds number, void fractions and blockage ratios. Two uniform experimental equations, were shown to describe the vortex shedding frequency f and pressure difference DeltaP between the front and rear stagnation points of the obstacle for various blockage ratios. An entirely new method for measuring the flow rate of the gas-liquid two-phase flow by f and DeltaP was shown.