The multimodular organization of the CNN proteins

被引：5

作者：

Perbal, B ^{[1
]}

机构：

[1] Univ Paris 07, UFR Biochim, F-75005 Paris, France

来源：

M S-MEDECINE SCIENCES | 2002年 / 18卷 / 6-7期

关键词：

D O I：

10.1051/medsci/20021867745

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The CCN family of genes and proteins is composed of key regulators involved in the control of cell growth in normal and pathological conditions. The CCN proteins are controling cell adhesion, motility and proliferation. In pathological conditions, such cis cancer development, the balance of negative and positive signals induced by these regulators is altered. In this review article we analyse the multimodular organization of the CCN proteins and discuss features that provide a structural basis for their multiple biological activities.

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页码：745 / 756

页数：12

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