Application of imiquimod by suppositories (anal tampons) efficiently prevents recurrences after ablation of anal canal condyloma

被引：57

作者：

Kaspari, M ^{[1
]}

Gutzmer, R ^{[1
]}

Kaspari, T ^{[1
]}

Kapp, A ^{[1
]}

Brodersen, JP ^{[1
]}

机构：

[1] Hannover Med Univ, Dept Dermatol & Allergol, D-30449 Hannover, Germany

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2002年 / 147卷 / 04期

关键词：

anal canal condyloma; condylomata acuminata; imiquimod; therapy;

D O I：

10.1046/j.1365-2133.2002.04979.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background After surgical removal, anal canal condyloma (ACC) has a higher risk of recurrence compared with extragenital warts. Objectives To reduce local recurrences of ACC using follow-up treatment with imiquimod-containing suppositories (anal tampons). Methods After ablation of ACC, 10 male patients received treatment with imiquimod suppositories three times weekly for 3-4 months. Results Treatment with imiquimod anal tampons was well tolerated. Early initial recurrences in some patients cleared after treatment with the imiquimod suppositories. Within a mean follow-up of 9 months no patient demonstrated recurrence of ACC. Conclusions These data suggest that imiquimod anal tampons may represent a new therapeutic option to prevent recurrences of ACC following ablative surgery.

引用

页码：757 / 759

页数：3