Marine polysaccharide-based nanomaterials as a novel source of nanobiotechnological applications

被引:145
作者
Manivasagan, Panchanathan [1 ]
Oh, Junghwan [1 ,2 ,3 ]
机构
[1] Pukyong Natl Univ, Marine Integrated Bion Res Ctr, Busan 608737, South Korea
[2] Pukyong Natl Univ, Dept Biomed Engn, Busan 608737, South Korea
[3] Pukyong Natl Univ, Ctr Marine Integrated Biotechnol Plus BK21, Busan 608737, South Korea
关键词
Marine polysaccharides; Nanomaterials; Biomedical applications; Nanoparticles; Drug delivery; DRUG-DELIVERY-SYSTEM; CHITOSAN NANOPARTICLES; SILVER NANOPARTICLES; SULFATED POLYSACCHARIDE; ALGINATE NANOPARTICLES; CHITIN NANOPARTICLES; ANTITUMOR-ACTIVITY; CHITOSAN/CARRAGEENAN NANOPARTICLES; ANTIOXIDANT ACTIVITIES; ANTITUBERCULAR DRUGS;
D O I
10.1016/j.ijbiomac.2015.10.081
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
Research on marine polysaccharide-based nanomaterials is emerging in nanobiotechnological fields such as drug delivery, gene delivery, tissue engineering, cancer therapy, wound dressing, biosensors, and water treatment. Important properties of the marine polysaccharides include biocompatibility, biodegradability, nontoxicity, low cost, and abundance. Most of the marine polysaccharides are derived from natural sources such as fucoidan, alginates, carrageenan, agarose, porphyran, ulvan, mauran, chitin, chitosan, and chitooligosaccharide. Marine polysaccharides are very important biological macromolecules that widely exist in marine organisms. Marine polysaccharides exhibit a vast variety of structures and are still under-exploited and thus should be considered as a novel source of natural products for drug discovery. An enormous variety of polysaccharides can be extracted from marine organisms such as algae, crustaceans, and microorganisms. Marine polysaccharides have been shown to have a variety of biological and biomedical properties. Recently, research and development of marine polysaccharide-based nanomaterials have received considerable attention as one of the major resources for nanotechnological applications. This review highlights the recent research on marine polysaccharide-based nanomaterials for biotechnological and biomedical applications. (c) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:315 / 327
页数:13
相关论文
共 134 条
[1]
Recent advances on chitosan-based micro- and nanoparticles in drug delivery [J].
Agnihotri, SA ;
Mallikarjuna, NN ;
Aminabhavi, TM .
JOURNAL OF CONTROLLED RELEASE, 2004, 100 (01) :5-28
[2]
Chemotherapeutic evaluation of alginate nanoparticle-encapsulated azole antifungal and antitubercular drugs against murine tuberculosis [J].
Ahmad, Zahoor ;
Sharma, Sadhna ;
Khuller, Gopal K. .
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2007, 3 (03) :239-243
[3]
Pharmacokinetic and pharmacodynamic behaviour of antitubercular drugs encapsulated in alginate nanoparticles at two doses [J].
Ahmad, Zahoor ;
Pandey, Rajesh ;
Sharma, Sadhna ;
Khuller, Gopal K. .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2006, 27 (05) :409-416
[4]
Synthesis and characterization of chitosan and silver loaded chitosan nanoparticles for bioactive polyester [J].
Ali, S. Wazed ;
Rajendran, S. ;
Joshi, Mangala .
CARBOHYDRATE POLYMERS, 2011, 83 (02) :438-446
[5]
The Use of Nanoparticles to Control Oral Biofilm Formation [J].
Allaker, R. P. .
JOURNAL OF DENTAL RESEARCH, 2010, 89 (11) :1175-1186
[6]
Anh N.T., 2010, RADIAT PHYS CHEM, V79, P405, DOI DOI 10.1016/J.RADPHYSCHEM.2009.11.013
[7]
Chitosan Oligosaccharide-Stabilized Ferrimagnetic Iron Oxide Nanocubes for Magnetically Modulated Cancer Hyperthermia [J].
Bae, Ki Hyun ;
Park, Mihyun ;
Do, Min Jae ;
Lee, Nohyun ;
Ryu, Ji Hyun ;
Kim, Gun Woo ;
Kim, CheolGi ;
Park, Tae Gwan ;
Hyeon, Taeghwan .
ACS NANO, 2012, 6 (06) :5266-5273
[8]
Preparation, characterization and biodistribution of ultrafine chitosan nanoparticles [J].
Banerjee, T ;
Mitra, S ;
Singh, AK ;
Sharma, RK ;
Maitra, A .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2002, 243 (1-2) :93-105
[9]
Conformation of sulfated galactan and sulfated fucan in aqueous solutions: Implications to their anticoagulant activities [J].
Becker, Camila F. ;
Guimaraes, Jorge A. ;
Mourao, Paulo A. S. ;
Verli, Hugo .
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2007, 26 (01) :391-399
[10]
Sulfated fucans, fresh perspectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide [J].
Berteau, O ;
Mulloy, B .
GLYCOBIOLOGY, 2003, 13 (06) :29R-40R