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Mood state and brain electric activity in Ecstasy users

被引：67
作者：
Gamma, A
Frei, E
Lehmann, D
Pascual-Marqui, RD
Hell, D
Vollenweider, FX
机构：
[1] Univ Hosp Psychiat, Res Unit, CH-8029 Zurich, Switzerland
[2] Univ Hosp Psychiat, KEY Inst Brain Mind Res, CH-8029 Zurich, Switzerland
来源：
NEUROREPORT | 2000年 / 11卷 / 01期
关键词：
drug abuse; Ecstasy; EEG; LORETA; MDMA; mood;
D O I：
10.1097/00001756-200001170-00031
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Resting EEG during open and dosed eyes and subsequent mood ratings were obtained from 15 Ecstasy users and 14 Ecstasy-naive controls. Absolute spectral power on the scalp, and the three-dimensional, intracerebral distribution of neuroelectric activity using low resolution brain electromagnetic tomography (LORETA) were computed. LORETA revealed global increases of theta, alpha I and beta2/3 power during eyes open in Ecstasy users, and spectral analyses revealed a right-posterior increase of alpha2 power (confirmed by LORETA) and increased beta band activity during open eyes. Ecstasy users had higher levels of stare depressiveness, emotional excitability and a trend-level increase in state anxiety. The observed differences may be related to regular exposure to Ecstasy or other illicit drugs,or may be pre-existing. NeuroReport 11:157-162 (C) 2000 Lippincott Williams & Wilkins.
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页码：157 / 162
页数：6
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