Mood state and brain electric activity in Ecstasy users

被引：67

作者：

Gamma, A

Frei, E

Lehmann, D

Pascual-Marqui, RD

Hell, D

Vollenweider, FX

机构：

[1] Univ Hosp Psychiat, Res Unit, CH-8029 Zurich, Switzerland

[2] Univ Hosp Psychiat, KEY Inst Brain Mind Res, CH-8029 Zurich, Switzerland

来源：

NEUROREPORT | 2000年 / 11卷 / 01期

关键词：

drug abuse; Ecstasy; EEG; LORETA; MDMA; mood;

D O I：

10.1097/00001756-200001170-00031

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Resting EEG during open and dosed eyes and subsequent mood ratings were obtained from 15 Ecstasy users and 14 Ecstasy-naive controls. Absolute spectral power on the scalp, and the three-dimensional, intracerebral distribution of neuroelectric activity using low resolution brain electromagnetic tomography (LORETA) were computed. LORETA revealed global increases of theta, alpha I and beta2/3 power during eyes open in Ecstasy users, and spectral analyses revealed a right-posterior increase of alpha2 power (confirmed by LORETA) and increased beta band activity during open eyes. Ecstasy users had higher levels of stare depressiveness, emotional excitability and a trend-level increase in state anxiety. The observed differences may be related to regular exposure to Ecstasy or other illicit drugs,or may be pre-existing. NeuroReport 11:157-162 (C) 2000 Lippincott Williams & Wilkins.

引用

页码：157 / 162

页数：6

共 24 条

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