Total synthesis of (+)-phyllantidine

被引：115

作者：

Carson, Cheryl A. ^{[1
]}

Kerr, Michael A. ^{[1
]}

机构：

[1] Univ Western Ontario, Dept Chem, London, ON N6A 5B7, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 39期

关键词：

alkaloids; cycloaddition; nitrone; oxazine; total synthesis;

D O I：

10.1002/anie.200602569

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three into one will go! A three-component coupling of a hydroxylamine, an aldehyde, and a cyclopropane diester provides the tetrahydro-1,2-oxazine scaffold necessary for completion of the first total synthesis of the natural product phyllantidine. (Figure Presented) © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6560 / 6563

页数：4

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