Exploiting the Divergent Reactivity of Aryl-Palladium Intermediates for the Rapid Assembly of Fluorene and Phenanthrene Derivatives

被引：141

作者：

Zhao, Ya-Bin ^{[1
]}

Mariampillai, Brian ^{[1
]}

Candito, David A. ^{[1
]}

Laleu, Benoit ^{[1
]}

Li, Mengzhou ^{[1
]}

Lautens, Mark ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 10期

基金：

瑞士国家科学基金会; 加拿大自然科学与工程研究理事会;

关键词：

annulation; C-H activation; domino reactions; homogeneous catalysis; palladium; INTRAMOLECULAR NUCLEOPHILIC-ADDITION; CATALYZED ALPHA-ARYLATION; ARYLBORONIC ACIDS; SUZUKI-MIYAURA; KETONES; ALKYNES; CYCLIZATION; SUBSTITUTION; ANNULATION; COMPLEXES;

D O I：

10.1002/anie.200805780

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

They all fall down: The value of domino processes can be greatly enhanced when the possibility exists for one to selectively diverge from a common intermediate. In preliminary studies the dual reactivity of aryl-palladium intermediates is exploited. A diverse array of fluorene and phenanthrene derivatives were synthesized in a rapid and efficient manner (see scheme). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1849 / 1852

页数：4

共 44 条

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Ackermann L., 2006, Angew. Chem, V118, P7789

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