The evolution of HIV and its consequences

被引：13

作者：

Apetrei, C

Marx, PA

Smith, SM

机构：

[1] St Michaels Hosp, Newark, NJ 07102 USA

[2] Univ Med & Dent New Jersey, Newark, NJ 07102 USA

[3] Tulane Natl Primate Res Ctr, Covington, LA 70433 USA

[4] Tulane Univ, Hlth Sci Ctr, Dept Trop Med, Covington, LA 70433 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2004年 / 18卷 / 02期

关键词：

D O I：

10.1016/j.idc.2004.01.010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Since the beginning of the AIDS epidemic in 198 1, HIV-1 has demonstrated an amazing ability to mutate. HIV-1 was introduced into the human population in the early to mid twentieth century in central Africa. During ensuing decades, this extraordinary mutational capacity has resulted in the circulation of HIV-1 strains that are quite different from one another, yet still remarkably pathogenic. The potential impact of this viral diversity on treatment, monitoring, and vaccine development is discussed.

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页码：369 / +

页数：27

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